HKClinicalTrials.com provides information about clinical research in human volunteers which is regularly updated. In addition, you will also find information about the purpose of a clinical trial, who may participate, locations, and phone numbers of who to contact.

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Browse all - all registered studies

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Search - search through all registered studies

Trial Information Submission
Download Online Study Registration Form

Resource Information
US clinical trial registry
GCP training
Understanding Clinical Trials - information explaining and describing clinical trials

 Useful Links
Clinical Trials Centre, The University of Hong Kong - the Hong Kong Academic Research Organization
ClinCluster - the Hong Kong Clinical Trial Network
The University of Hong Kong / Hospital Authority Hong Kong West Cluster IRB
Hospital Authority Research Ethics Committee
ICMJE - Questions about Clinical Trials Registration

Audit Trail
An audit trail of all changes to any of the data contained in the HKClinicalTrials.com database will be maintained by the Clinical Trials Centre. For further information about the audit trail please contact: hkuctreg@hku.hk

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Clinical Trials Registry online register therapeutic areas trials pharmaceuticals, surgical procedures, preventive measures, lifestyle, devices, treatment rehabilitation strategies complementary therapies participants traditional Chinese medicine TCM DIA GCP ICH enrolment patient phase I phase II phase III phase IV register website required data submitting trial registration Publicly owned, managed by a not-for-profit organisation Registration voluntary Responsibility Sponsor intervention comparison medical intervention health outcome Exploratory studies sample size treatments investigation outcomes assessed principal investigators new england journal of medicine jama lancet International Committee of Medical Journal Editors (ICMJE) World Health Organization (WHO) Fair Access to Clinical Trials (FACT) www.clinicaltrials.gov ClinicalTrials.gov provides regularly updated information about federally and privately supported clinical research in human volunteers ClinicalTrialsgov gives you information about a trial's purpose, who may participate, locations, and phone numbers for more details The information provided on ClinicalTrials.gov should be used in conjunction with advice from health care professionals International Clinical Trials Registry Platform Clinical trials are one of the most important sources of scientific evidence on the safety and effectiveness of health interventions Access to information about ongoing, completed and published clinical trials is essential for appropriate decision-making Researchers, research funders, policy-makers, medical practitioners, patients and the general public need such information, to help guide research or to make treatment decisions To ensure transparency and to increase public trust in the conduct of clinical research, it is important that all clinical trials be registered at inception and that all results be made publicly available With the approval of the World Health Assembly in May of 2005, the International Clinical Trials Registry Platform is taking the lead in setting international norms and standards for trial registration and reporting The Registry Platform consults with relevant stakeholders worldwide to produce consensus-based policies that uphold scientific and ethical principles on clinical trials but that are also practical and feasible The Registry Platform's primary objectives are to ensure that all clinical trials are registered and thus publicly declared and identifiable, so as to ensure that for all trials, a minimum set of results will be reported and made publicly available Specific goals of the Registry Platform include establishing standards on the scope and content of trial registration, establishing a network of Member Registers that satisfy criteria for internationally acceptable registers, establishing and assigning a Universal Trial Reference Number to globally unique trials, defining minimum standards for the reporting of trial results, and launching a one-stop Search Portal for searching registers worldwide The WHO does not plan to offer a WHO-administered register Therefore, trialists should keep on registering with existing registers Please check this website regularly for updates on progress A clinical trial (also clinical research) is a research study in human volunteers to answer specific health questions. Carefully conducted clinical trials are the fastest and safest way to find treatments that work in people and ways to improve health. Interventional trials determine whether experimental treatments or new ways of using known therapies are safe and effective under controlled environments. Observational trials address health issues in large groups of people or populations in natural settings CONTROLLED TRIALS Control is a standard against which experimental observations may be evaluated. In clinical trials, one group of participants is given an experimental drug, while another group (i.e., the control group) is given either a standard treatment for the disease or a placebo. DATA SAFETY AND MONITOR prevention PREVENTION TRIALS Refers to trials to find better ways to prevent disease in people who have never had the disease or to prevent a disease from returning. These approaches may include medicines, vitamins, vaccines, minerals, or lifestyle changes. PROTOCOL: A study plan on which all clinical trials are based. The plan is carefully designed to safeguard the health of the participants as well as answer specific research questions. A protocol describes what types of people may participate in the trial; the schedule of tests, procedures, medications, and dosages; and the length of the study. While in a clinical trial, participants following a protocol are seen regularly by the research staff to monitor their health and to determine the safety and effectiveness of their treatment QUALITY OF LIFE TRIALS (or Supportive Care trials): Refers to trials that explore ways to improve comfort and quality of life for individuals with a chronic illness. RANDOMIZATION A method based on chance by which study participants are assigned to a treatment group. Randomization minimizes the differences among groups by equally distributing people with particular characteristics among all the trial arms. The researchers do not know which treatment is better. From what is known at the time, any one of the treatments chosen could be of benefit to the participant RANDOMIZED TRIAL A study in which participants are randomly (i.e., by chance) assigned to one of two or more treatment arms of a clinical trial. Occasionally placebos are utilizedThe risk to individual participants versus the potential benefits. The risk benefit ratio may differ depending on the condition being treated. SCREENING TRIALS Refers to trials which test the best way to detect certain diseases or health conditions. SIDE EFFECTS Any undesired actions or effects of a drug or treatment. Negative or adverse effects may include headache, nausea, hair loss, skin irritation, or other physical problems. Experimental drugs must be evaluated for both immediate and long-term side SINGLE-BLIND STUDY A study in which one party, either the investigator or participant, is unaware of what medication the participant is taking; also called single-masked study. SINGLE-MASKED STUDY STANDARD TREATMENT A treatment currently in wide use and approved by the FDA, considered to be effective in the treatment of a specific disease or condition. STANDARDS OF CARE Treatment regimen or medical management based on state of the art participant care. STATISTICAL SIGNIFICANCE The probability that an event or difference occurred by chance alone. In clinical trials, the level of statistical significance depends on the number of participants studied and the observations made, as well as the magnitude of differences observed. STUDY ENDPOINT A primary or secondary outcome used to judge the effectiveness of a treatment. STUDY TYPE The primary investigative techniques used in an observational protocol; types are Purpose, Duration, Selection, and Timing. TOXICITY: An adverse effect produced by a drug that is detrimental to the participant's health. The level of toxicity associated with a drug will vary depending on the condition which the drug is used to treat. TREATMENT IND : IND stands for Investigational New Drug application, which is part of the process to get approval from the FDA for marketing a new prescription drug in the U.S. It makes promising new drugs available to desperately ill participants as early in the drug development process as possible. Treatment INDs are made available to participants before general marketing begins, typically during Phase III studies. To be considered for a treatment IND a participant cannot be eligible to be in the definitive clinical trial. TREATMENT TRIALS Refers to trials which test new treatments, new combinations of drugs, or new approaches to surgery or radiation therapy.